Peptide Synthesis
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Author:jienitai
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Published time: 2018-12-25
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Custom Peptide Synthesis Service
GenicBio offers custom peptides of the highest quality, at the most competitive price. Our staff has decade of intensive experience in the design, synthesis and production of peptides using Fmoc solid phase and solution phase technology. All peptides are purified using HPLC and analyzed by mass spectrometry and the reports will be provided to customers.
Every year over thousands of custom peptides are provided to worldwide customers,most custom peptides can be delivered within 2~3 weeks after receipt and confirmation of your order.
Services Features
• Custom synthesis from 2-120 amino acids in length
• High quality peptides from mg to kg
• Purities from crude to 98% or higher
• Peptide antigen design for antibody development
• Success rate >98%
• Extremely competitive pricing for all of our peptides
• In stock beta-amyloid peptides (Beta-amyloid 1-40 & Beta-amyloid 1-42) and many other common peptides for immediate delivery
• An extensive list of labeling and modification: : including biotinylation, S-S disulfide bonds, cyclization, phosphorylation and fluorescence dye labeling etc.
Deliverables and Delivery Times:
• All peptides supplied with Mass Spec and RP-HPLC data
• Our typical turn-around time is about 2~3 weeks.
• Shipping carrier is FedEx or DHL, for international delivery, it usually takes 3-4 days.
• All peptides are shipped as lyophilized powder
Custom Peptide Synthesis Quotation and Order information
Since custom peptide prices vary upon peptide length, purity and scale, we recommend submitting a quotation by email (service@genicbio.com) for obtaining an accurate price.
The quoted price will depend on:
1, The length of the peptide and the amino acid composition
2, Unnatural amino acids, amino acid derivatives
3, Peptide modifications
4, Required purity level e.g. crude, >70%, >75%, >80%, >85%, >90%, >95% or >98% on the basis of HPLC analysis
5, Quantity: from 1mg to kilogram scales.
In general the customer's request will be quoted within 24 hours.
For preparing a quotation we need some information about the peptides to be synthesized:
1) Sequence of the amino acids
2) N-terminus of the peptide (e.g. free or acetyl)
3) C-terminus of the peptide (e.g. amide or carboxyl)
4) Amount (e.g. 1mg, 5mg, 10 mg, 50 mg, 100 mg...)
5) Purity (e.g. crude, >70%, >75%, >80%, >85%, >90%, >95% or >98%)
Peptide Modifications
Our workers are experienced in the synthesis of high quality peptides with various modifications, below is a partial list of peptide modification we offer. For modification not found in the list, please email us for a quote.
Selected References:
GenicBio offers custom peptides of the highest quality, at the most competitive price. Our staff has decade of intensive experience in the design, synthesis and production of peptides using Fmoc solid phase and solution phase technology. All peptides are purified using HPLC and analyzed by mass spectrometry and the reports will be provided to customers.
Every year over thousands of custom peptides are provided to worldwide customers,most custom peptides can be delivered within 2~3 weeks after receipt and confirmation of your order.
Services Features
• Custom synthesis from 2-120 amino acids in length
• High quality peptides from mg to kg
• Purities from crude to 98% or higher
• Peptide antigen design for antibody development
• Success rate >98%
• Extremely competitive pricing for all of our peptides
• In stock beta-amyloid peptides (Beta-amyloid 1-40 & Beta-amyloid 1-42) and many other common peptides for immediate delivery
• An extensive list of labeling and modification: : including biotinylation, S-S disulfide bonds, cyclization, phosphorylation and fluorescence dye labeling etc.
Deliverables and Delivery Times:
• All peptides supplied with Mass Spec and RP-HPLC data
• Our typical turn-around time is about 2~3 weeks.
• Shipping carrier is FedEx or DHL, for international delivery, it usually takes 3-4 days.
• All peptides are shipped as lyophilized powder
Custom Peptide Synthesis Quotation and Order information
Since custom peptide prices vary upon peptide length, purity and scale, we recommend submitting a quotation by email (service@genicbio.com) for obtaining an accurate price.
The quoted price will depend on:
1, The length of the peptide and the amino acid composition
2, Unnatural amino acids, amino acid derivatives
3, Peptide modifications
4, Required purity level e.g. crude, >70%, >75%, >80%, >85%, >90%, >95% or >98% on the basis of HPLC analysis
5, Quantity: from 1mg to kilogram scales.
In general the customer's request will be quoted within 24 hours.
For preparing a quotation we need some information about the peptides to be synthesized:
1) Sequence of the amino acids
2) N-terminus of the peptide (e.g. free or acetyl)
3) C-terminus of the peptide (e.g. amide or carboxyl)
4) Amount (e.g. 1mg, 5mg, 10 mg, 50 mg, 100 mg...)
5) Purity (e.g. crude, >70%, >75%, >80%, >85%, >90%, >95% or >98%)
Peptide Modifications
Our workers are experienced in the synthesis of high quality peptides with various modifications, below is a partial list of peptide modification we offer. For modification not found in the list, please email us for a quote.
| N,C-terminal Modification | Special Amino acid | Fluorescence/Dye labeling | Cyclic Peptide | Quenched Fluorescent Peptide | Phosphorylation | Protein Conjugation |
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Acetylation, N-terminal
Amidation, C-terminal HYNIC, N-terminal DTPA, N-terminal Formylation, N-terminal Fatty acid, N-terminal Myristic acid, N-terminal Palmytolyl, N-terminal Benzyloxycarbonylation (CBZ) Succinylation (Suc, N-terminal) |
D-Arg, D-Cys, D-Asp,
D-Asn, D-Glu, D-Gln, D-Ser, D-His, D-Thr, D-Trp, D-Leu,D-Ile, D-Met,
D-Pro, D-Val ,D-Phe, pGlu, Hyp, D-Lys,D-Tyr, D-Orn, Orn, Abu, Aib,
(D)1-Nal, (D)2-Pal, (D)4-Cl-Phe, Nva, Nle, Hse, Hcy, Pen, Mpa,N-Methyl
amino acid (Ala, Phe, Leu, Ile, Val, Gly, Met),Other amino acid,
Dinitrobenzoylation (Lys), Lys(Me2), Phosphorylation (Tyr,
Ser, Thr, single site), Tyr(SO3H2), Ser(octanoic
acid)
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Biotin, N-terminal
Biotin, Lys side chain FITC, N-terminal FITC, Lys side chain 5-FAM, N-terminal 5-FAM, Lys side chain Dansyl, N-terminal MCA, N-terminal p-Nitroanilide(pNA, C-terminal) AMC, C-terminal |
Disulfide bond (1)
Disulfide bond (2) Disulfide bond (3)Amide cyclic (Side chain, end) |
Abz/ Tyr (3-NO2),
EDANS/DABCYL |
pSer
pThr pTyr |
KLH
BSA OVA MAP |
Selected References:
| T. T. Nha Tran etc. | Diagnostic cyclisation reactions which follow phosphate transfer to carboxylate anion centres for energised [M–H]– anions of pTyr‐containing peptides | 2011 |
| Dorothea Nillius etc. | Nitroreductase (GlNR1) increases susceptibility of Giardia lamblia and Escherichia coli to nitro drugs | 2011 |
| NV Kovalevskaya, FM Bokhovchuk | The TRPV5/6 calcium channels contain multiple calmodulin binding sites with differential binding properties | 2012 |
| Doktors der Medizin | Einfluss der sauren Sphingomyelinase auf die Makrophagenaktivierung durch Alzheimer Amyloid Protein | 2012 |
| Eleonora Margheritis, etc. | Characterization of the transport of lysine-containing dipeptides by PepT1 orthologs expressed in Xenopus laevis oocytes | 2013 |
| K.E.Cervantes-Luevano, etc. | Effect of two synthetic disulfide bond variants of a 13-mer toxin from Conus californicus on the transcription of pro-inflammatory cytokines induced by LPS | 2013 |
| T. T. Nha Tran, etc. | Fragmentations of [M − H]− anions of peptides containing tyrosine sulfate. Does the sulfate group rearrange? A joint experimental and theoretical study | 2013 |
| Lucas J. Sosa, Nienke L. Postma, etc. | Dosage of amyloid precursor protein affects axonal contact guidance in Down syndrome | 2014 |
| Lakshmanane Premkumar, Fabian Kurth, etc. | Structure of the Acinetobacter baumannii Dithiol Oxidase DsbA Bound to Elongation Factor EF-Tu Reveals a Novel Protein Interaction Site | 2014 |
| Chang-Fang Wang, Hélder A. Santos, etc. | Copper-Free Click Chemistry Modification of Nanovectors for Integrin-Targeted Cancer Therapy | 2015 |
| Anuja P Kawle, Amit R Nayak, etc. | Comparative evaluation of risk factors, outcome and biomarker levels in young and old acute ischemic stroke patients | 2015 |
| Sravan Pandalaneni,Vijaykumar Karuppiah, etc. | Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions* | 2015 |
| Alison A. Jack, Debbie E. Daniels, etc. | Streptococcus gordonii comCDE (competence) operon modulates biofilm formation with Candida albicans | 2015 |
| Lamesh Ramdani, Romain Bourboulou | Multifunctional Curcumin-Nanocarriers Based on Host-Guest Interactions for Alzheimer Disease Diagnostic | 2015 |
| Miha Pavšič, Gregor Ilc, etc. | The cytosolic tail of the tumor marker protein Trop2 - a structural switch triggered by phosphorylation | 2015 |
| Gustavo Núñez-Acuña, Jorge PinoMarambio | Antimicrobial peptides from Salmon salar skin induce frontal filament development and olfactory/cuticle-related genes in the sea louse Caligus rogercresseyi | 2016 |
| Erik D. Guetschow, Surinder Kumar, etc. | Identification of sirtuin 5 inhibitors by ultrafast microchip electrophoresis using nanoliter volume samples | 2016 |
| Mikaela Grönholm, Farhana Jahan, etc. | LFA-1 integrin antibodies inhibit leukocyte α4β1–mediated adhesion by intracellular signaling | 2016 |
| Guoying Ni, Shu Chen, Yuedong Yang | Investigation the Possibility of Using Peptides with a Helical Repeating Pattern of Hydro-Phobic and Hydrophilic Residues to Inhibit IL-10 | 2016 |
| Smith, A. Ian, Rajapakse, Niwanthi W. | N-terminal peptide of myotoxin II from Bothrops asper venom enhances the activity of endothelin converting enzyme and neprilysin | 2016 |
| Neha H. Lande, Amit R. Nayak, etc. | Assessment of Inter-alpha-trypsin heavy chain-4 peptides in differential diagnosis of ischemic and hemorrhagic stroke | 2017 |
| Peisheng Zhang， Xuezheng Nie， Meng Gao, etc. | A highly selective fluorescent nanoprobe based on AIE and ESIPT for imaging hydrogen sulfide in live cells and zebrafish† | 2017 |
| Pedro F Teixeira, Beata Kmiec, Rui M M Branca, etc. | A multi-step peptidolytic cascade for amino acid recovery in chloroplasts | 2017 |
| P. P. S. Pannu, Jaspal Kaur, etc. | Understanding Bakanae: a major threat and an emerging disease of Basmati rice | 2018 |
| Santhosh Kalash Rajendrakumar, etc. | Dual-stimuli-responsive albumin-polyplex nanoassembly for spatially controlled gene release in metastatic breast cancer | 2018 |
| Marisa Pereira,Diogo Tomé, etc. | A Fluorescence‐Based Sensor Assay that Monitors General Protein Aggregation in Human Cells | 2018 |
| DavorJuretić, YogeshSonavane, etc. | Designed peptide with a flexible central motif from ranatuerins adapts its conformation to bacterial membranes | 2018 |
| Rita N. Straus Rebecca A. Jockusch | Hydrogen-Deuterium Exchange and Electron Capture Dissociation to Interrogate the Conformation of Gaseous Melittin Ions | 2019 |
| Bincy Bhask,raLaxmi Ananthanarayan, etc. | Purification, identification, and characterization of novel angiotensin I-converting enzyme (ACE) inhibitory peptides from alcalase digested horse gram flour | 2019 |
| Kondareddy Cherukula, Saji Uthaman | Design of an Amphiphilic Poly(aspartamide)-Mediated Self-Assembled Nanoconstruct for Long-Term Tumor Targeting and Bioimaging | 2019 |
| Monica Terracciano, Luca De Stefano, etc. | In Vivo Toxicity Assessment of Hybrid Diatomite Nanovectors Using Hydra vulgaris as a Model System | 2019 |
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